PMS2抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
PMS2抗体

PMS2抗体

商家询价

产品名称： PMS2抗体

英文名称： PMS2Antibody

产品编号： XY18164-1-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
  • 联系人 : 徐经理
  • 地址 : 上海市闵行莘庄工业区春东路508号A1-2F
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 152****8802 点击查看
  • 传真 : 点击查看
  • 邮箱 : shxysw02@163.com
  • 二维码 : 点击查看
进入展台

 PMS2抗体Applications

In-house applications ELISA, WB     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
Images
Prev1NextView more validation data
  • 18164-1-AP;A431 cellA431 cells were subjected to SDS PAGE followed by western blot with 18164-1-AP(PMS2 antibody) at dilution of 1:500
Positive WB detected in A431 cells, HeLa cells, HT-1080 cells, MCF7 cells, PC-3 cells, Raji cells
Recommended dilution WB : 1:200-1:2000
 PMS2抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen PMS2 fusion protein ag12651 Full name PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
Calculated molecular
weight		 862aa,96 kDa Observed molecular 
weight		 117 kDa,100 kDa
GenBank accession 
number		 BC093921 Gene ID (NCBI) 5395
Gene symbol PMS2 Synonyms HNPCC4, PMS1 protein homolog 2, PMS2, PMS2CL, PMSL2
Background PMS2抗体

PMS2, also named as PMSL2, belongs to the DNA mismatch repair mutL/hexB family. It is a component of the post-replicative DNA mismatch repair system (MMR). It heterodimerizes with MLH1 to form MutL alpha. MulL alpha (MLH1-PMS2) interacts physically with the clamp loader subunits of DNA polymerase III, suggesting that it may play a role to recruit the DNA polymerase III to the site of the MMR. It also implicated in DNA damage signaling, a process which induces cell cycle arrest and can lead to apoptosis in case of major DNA damages. (PMID: 16873062, PMID: 18206974) Defects in PMS2 are the cause of hereditary non-polyposis colorectal cancer type 4 (HNPCC4). Defects in PMS2 are a cause of mismatch repair cancer syndrome (MMRCS). This antibody is specific to PMS2. PMS2抗体

XY255Hu21 脯氨酰4-羟化酶α多肽Ⅲ(P4Hα3)单克隆抗体 Monoclonal Antibody to Prolyl-4-Hydroxylase Alpha Polypeptide III (P4Ha3) Homo sapiens (Hukl)

XY256Hu21 前胶原赖氨酸-1,2-酮戊二酸-5-双加氧酶1(PLOD1)单克隆抗体 Monoclonal Antibody to Procollagen Lysine-1,2-Oxoglutarate-5-Dioxygenase 1 (PLOD1) Homo sapiens (Hukl)

XY257Hu21 前胶原赖氨酸-2-酮戊二酸-5-双加氧酶1(PLOD2)单克隆抗体 Monoclonal Antibody to Procollagen Lysine-2-Oxoglutarate-5-Dioxygenase 2 (PLOD2) Homo sapiens (Hukl)

XY258Hu21 前胶原赖氨酸-2-酮戊二酸-5-双加氧酶1(PLOD3)单克隆抗体 Monoclonal Antibody to Procollagen Lysine-2-Oxoglutarate-5-Dioxygenase 3 (PLOD3) Homo sapiens (Hukl)

XY260Hu21 色氨酸-2,3-双加氧酶(TDO)单克隆抗体 Monoclonal Antibody to Tryptophan-2,3-dioxygenase (TDO) Homo sapiens (Hukl)

XY269Hu21 B-淋巴酪氨酸激酶(BLK)单克隆抗体 Monoclonal Antibody to B-Lymphoid Tyrosine Kinase (BLK) Homo sapiens (Hukl)

XY270Hu21 骨骼肌特异性受体酪氨酸激酶(MUSK)单克隆抗体 Monoclonal Antibody to Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK) Homo sapiens (Hukl)

XY271Hu21 C-Mer原癌基因酪氨酸激酶(MERTK)单克隆抗体 Monoclonal Antibody to C-Mer Proto Oncogene Tyrosine Kinase (MERTK) Homo sapiens (Hukl)

XY273Ra21 C-Ros癌基因1(ROS1)单克隆抗体 Monoclonal Antibody to C-Ros Oncogene 1, Receptor Tyrosine Kinase (ROS1) Rattus norvegicus (Rat)

XY275Hu21 脾脏酪氨酸激酶(SYK)单克隆抗体 Monoclonal Antibody to Spleen Tyrosine Kinase (SYK) Homo sapiens (Hukl)

XY277Hu21 蛋白酪氨酸激酶6(PTK6)单克隆抗体 Monoclonal Antibody to Protein Tyrosine Kinase 6 (PTK6) Homo sapiens (Hukl)

XY279Ra21 唾液酸酶2(SIAL2)单克隆抗体 Monoclonal Antibody to Sialidase 2, Cytosolic (SIAL2) Rattus norvegicus (Rat)

XY293Hu21 Rac-GTP酶激活蛋白1(RACGAP1)单克隆抗体 Monoclonal Antibody to Rac-GTPase Activating Protein 1 (RACGAP1) Homo sapiens (Hukl)

XY320Hu21 Ras同源基因家族成员A(RHOA)单克隆抗体 Monoclonal Antibody to Ras Homolog Gene Family, Member A (RHOA) Homo sapiens (Hukl)

XY329Hu21 Rho GDP解离抑制因子α(ARHGDIα)单克隆抗体 Monoclonal Antibody to Rho GDP Dissociation Inhibitor Alpha (ARHGDIa) Homo sapiens (Hukl)

XY330Hu21 Rho GDP解离抑制因子β(ARHGDIβ)单克隆抗体 Monoclonal Antibody to Rho GDP Dissociation Inhibitor Beta (ARHGDIb) Homo sapiens (Hukl)

XY342Hu21 兴奋性氨基酸转运蛋白3(EAAT3)单克隆抗体 Monoclonal Antibody to Excitatory Amino Acid Transporter 3 (EAAT3) Homo sapiens (Hukl)

XY343Hu21 兴奋性氨基酸转运蛋白1(EAAT1)单克隆抗体 Monoclonal Antibody to Excitatory Amino Acid Transporter 1 (EAAT1) Homo sapiens (Hukl)

XY345Hu21 溶质载体家族1成员5(SLC1A5)单克隆抗体 Monoclonal Antibody to Solute Carrier Family 1, Member 5 (SLC1A5) Homo sapiens (Hukl)

XY346Hu21 兴奋性氨基酸转运蛋白2(EAAT2)单克隆抗体 Monoclonal Antibody to Excitatory Amino Acid Transporter 2 (EAAT2) Homo sapiens (Hukl)