MPZL2 抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
MPZL2 抗体

MPZL2 抗体

商家询价

产品名称： MPZL2 抗体

英文名称： MPZL2 Antibody

产品编号： XY11787-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 MPZL2 抗体

Applications
In-house applications ELISA, WB     Application not tested? Please see our Guarantee.
Published applications FC, IHC, WB Publications 4 citations –view here
Species specificity Human,Mouse,Rat; other species not tested.
Published Species Human, mouse
Images
Prev1NextView more validation data
  • 11787-1-AP;Jurkat cellJurkat cells were subjected to SDS PAGE followed by western blot with 11787-1-AP(MPZL2 antibody) at dilution of 1:800
Positive WB detected in Jurkat cells
Recommended dilution WB : 1:500-1:5000
MPZL2 抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen MPZL2 fusion protein ag2419 Full name Myelin protein zero-like 2
Calculated molecular
weight		 215aa,24 kDa Observed molecular 
weight		 24kd and 32kd
GenBank accession 
number		 BC017774 Gene ID (NCBI) 10205
Gene symbol MPZL2 Synonyms Epithelial V like antigen 1, EVA, EVA1, MPZL2, myelin protein zero like 2
BackgroundMPZL2 抗体

MPZL2 (myelin protein zero-like 2), also named as EVA (epithelial V-like antigen) or EVA1, is a type 1 transmembrane protein of the myelin P0 protein family, containing an Ig-like V-type (immunoglobulin-like) domain and two potential glycosylation sites. MPZL2 is expressed in thymus epithelium and strongly downregulated by thymocyte developmental progression. Its capacity to mediate cell adhesion through a homophilic interaction and its selective regulation by T cell maturation might imply the participation of EVA in the earliest phases of thymus organogenesis. The gene of MPZL2 maps to chromosome 11q24, and encodes a 215-amino acid protein with a predicted unmodified molecular weight of 24.5 kDa. This antibody can be used to detect endogenous MPZL2, however, the reason for the additional band of 32 kDa is still unknown.MPZL2 抗体

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