GIMAP5抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
GIMAP5抗体

GIMAP5抗体

商家询价

产品名称： GIMAP5抗体

英文名称： GIMAP5Antibody

产品编号： XY11068-1

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

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 GIMAP5抗体

Applications
In-house applications ELISA, WB, IHC     Application not tested? Please see our Guarantee.
Published applications WB Publications 2 citations –view here
Species specificity Human; other species not tested.
Published Species Human
Images
Prev1NextView more validation data
  • 11068-1-AP;Jurkat cellJurkat cells were subjected to SDS PAGE followed by western blot with 11068-1-AP(GIMAP5 antibody) at dilution of 1:500
  • 11068-1-AP;LymphomaImmunohistochemical of paraffin-embedded human lymphoma using 11068-1-AP(GIMAP5 antibody) at dilution of 1:50 (under 10x lens)
Positive WB detected in Jurkat cells, U-937 cells
Positive IHC detected in Human lymphoma tissue
Recommended dilution WB : 1:200-1:2000
IHC : 1:20-1:200
 GIMAP5抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.1% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen GIMAP5 fusion protein ag1509 Full name GTPase, IMAP family member 5
Calculated molecular
weight		 35 kDa Observed molecular 
weight		 45-50 kDa
GenBank accession 
number		 BC011732 Gene ID (NCBI) 55340
Gene symbol GIMAP5 Synonyms FLJ11296, GIMAP5, GTPase IMAP family member 5, GTPase, IMAP family member 5, hIAN5, HIMAP3, IAN 5, IAN4, IAN4L1, IAN5, IMAP3, Immunity associated protein 3
Background GIMAP5抗体

GIMAP5 gene encodes immunity-associated nucleotide 5 protein (IAN5) belonging to GTPase immune-associated protein subfamily. GIMAP5 is widely expressed with high levels in lymph node and spleen. The loss of Gimap5 (GTPase of the 5) gene function is the underlying cause of lymphopenia and autoimmune diabetes in the BioBreeding (BB) rat. Mouse gimap5 is necessary for the survival of peripheral T cells, NK/NKT-cell development, hematopoietic progenitor cell survival and the maintenance of normal liver function. GIMAP5 may regulate T lymphocyte survival by mechanisms that operate upstream of mitochondria. GIMAP5抗体

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